I had this nutty idea that I don't think would work in a game because of the intense stigma surrounding it, but it would be an internment camp simulator, so think a cross between Prison Architect and something like Frostpunk or Tropico.
Basically, the idea is you're a nation at war, so you stick citizens thought to be potentially disloyal and other dissidents in an internment camp, with all sort of facilities (farms, education facilities, hospitals, entertainment, etc.) all while putting them to work to create profit/weapons/food to fuel the war. Your goal is to grow the camp while the war wages on (there's a time limit, you have x years) and get enough resources to win the war.
While the idea is to remain profitable, there are several ways to go about this, you can create an ideal working environment for the residents, including leisure time (with things to do, so libraries, theaters, etc.) and plenty to eat to keep everyone happy and productive, or be incredibly cruel to people, have them work until they drop dead, feed them meat patties made with their own children, and inflict needless punishments just for the fun of it.
Could be both an interesting take on the city-sim genre and a psychological thought experiment at the same time.