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Yeah, but if you have explosive diarrhea, the half-melted suppository just shoots out before it's fully absorbed.It absorbs through the highly vascular area around your rectum, it's nothing to do with the motility of your digestive tract or ability of your small intestine to absorb medications. It's a great option for many types of medications, especially if people have nausea or vomiting.
Drug users have enjoyed absorbing drugs via their rectums for centuries.