Reminds me how the first game had a pretty brutal take on L.A. and Californication. Cool places were really just old husks of themselves (Santa Monica), the rich in lavish towers looking down on streets full of homeless and burning garbage (L.A. midtown), Hollywood was a astroturf wasteland with a creepy hypersexual undertone, and ethnic enclaves were crime-ridden slums ruled by powerful local despots who suppressed reform in the name of cultural tradition (Chinatown). It was so well-done and subtle that you didn't even question the bleakness. I doubt the new game would have anything interesting to say about the Pacific northwest, or worse, go the opposite way and rationalize the problems as a benefit. If you wanted a similar thing with Seattle, you'd have to come dangerously close to right wing talking points: tolerance of crime makes it harder for honest people to make a living, glorification of shallow personal expression stifling deeper spiritual individualism, disconnection between sex and relationships causing loneliness even as people engage in increasing debauchery, compassion becoming a crutch to enable cowardice instead of confronting problems, and belief in a permanent revolutionary movement acting as a antagonistic force to actual changes. Given how the good vampires (excuse me, the brujah) are a bunch of tatted up antifa throwing molotovs and the reeeing about Orange man, it's unlikely.