I also remembered that Sadie was a major part of the defense against the Pinkertons after Arthur returned from Guarma, is a part of the rescue of John from the Sisika Penitentiary where she kills many prison guards, takes part in the destruction of the Cornwall oil refinery and Army payroll train robbery, killing numerous US soldiers, then takes part in the misson to kill Milton, slaying even more agents.
Despite all this, in the epilogue there's no indication she's on the run from anyone. We can only speculate if she was killed or arrested, but nothing in the game indicates anything like that. Which is kind of shitty, because the games were all about the 'life' catching up to someone, yet in an effort to construct its girlboss character it completely contradicts that idea.
That's my primary criticism - It's one thing to make an annoying girl character and have other characters worship her, its another thing to spoil your primary message for the sake of dumb politics in a game that would be no different without her.