Wuhan Coronavirus: Megathread - Got too big

  • Want to keep track of this thread?
    Accounts can bookmark posts, watch threads for updates, and jump back to where you stopped reading.
    Create account
Status
Not open for further replies.
Super-Chevy454 said:
I won't be surprised if they sold it more costly than ivermecin.
Click to expand...
Without a doubt. While it would be hysterical for Merck to turn around and sell this "new" med for a few bucks, that won't make a profit which is part of the reason why ivermectin was discarded as a treatment option
 
Take your vaccine in pill form now

Article: https://longisland.news12.com/merck-says-experimental-pill-cuts-worst-effects-of-covid-19
Archive: https://archive.is/mPtJM
---------------------------------------------------
Merck says experimental pill cuts worst effects of COVID-19

Merck & Co. said Friday that its experimental COVID-19 pill (Archive: https://archive.is/8osQN ) reduced hospitalizations and deaths by half in people recently infected with the coronavirus and that it would soon ask health officials in the U.S. and around the world to authorize its use.

If cleared, Merck's drug would be the first pill shown to treat COVID-19, a potentially major advance in efforts to fight the pandemic. All COVID-19 therapies now authorized in the U.S. require an IV or injection.
Screenshot_2021-10-01_13-26-40.png

Merck and its partner Ridgeback Biotherapeutics said early results showed patients who received the drug, called molnupiravir, within five days of COVID-19 symptoms had about half the rate of hospitalization and death as patients who received a dummy pill. The study tracked 775 adults with mild-to-moderate COVID-19 who were considered higher risk for severe disease due to health problems such as obesity, diabetes or heart disease.

Among patients taking molnupiravir, 7.3% were either hospitalized or died at the end of 30 days, compared with 14.1% of those getting the dummy pill. There were no deaths in the drug group after that time period compared with eight deaths in the placebo group, according to Merck. The results were released by the company and have not been peer reviewed. Merck said it plans to present them at a future medical meeting.

An independent group of medical experts monitoring the trial recommended stopping it early because the interim results were so strong. Company executives said they are in discussions with the Food and Drug Administration and plan submit the data for review in coming days.

“It exceeded what I thought the drug might be able to do in this clinical trial,” said Dr. Dean Li, vice president of Merck research. “When you see a 50% reduction in hospitalization or death that’s a substantial clinical impact.”

Side effects were reported by both groups in the Merck trial, but they were slightly more common among the group that received a dummy pill. The company did not specify the problems.

Earlier study results showed the drug did not benefit patients who were already hospitalized with severe disease.

The U.S. has approved one antiviral drug, remdesivir, specifically for COVID-19, and allowed emergency use of three antibody therapies that help the immune system fight the virus. But all the drugs have to given by IV or injection at hospitals or medical clinics, and supplies have been stretched by the latest surge of the delta variant.

Health experts including the top U.S. infectious disease expert Dr. Anthony Fauci have long called for a convenient pill that patients could take when COVID-19 symptoms first appear, much the way the decades-old flu medication Tamiflu helps fight influenza. Such medications are seen as key to controlling future waves of infection and reducing the impact of the pandemic.

Merck’s pill works by interfering with an enzyme the coronavirus uses to copy its genetic code and reproduce itself. It has shown similar activity against other viruses.

The U.S. government has committed to purchase 1.7 million doses of the drug if it is authorized by the FDA. Merck has said it can produce 10 million doses by the end of the year and has contracts with governments worldwide. The company has not announced prices.

Several other companies, including Pfizer and Roche, are studying similar drugs that could report results in the coming weeks and months.

Merck had planned to enroll more than 1,500 patients in its late-stage trial before the independent board stopped it early. The results reported Friday included patients enrolled across Latin America, Europe and Africa. Executives estimated about 10% of patients studied were from the U.S.
---------------------------------------------------
 
teriyakiburns said:
Merck hold the patents on ivermectin. This new drug is literally just ivermectin with a tweak.
Click to expand...
It's not, just compare structures of molnupiravir and ivermectin, they are vastly different. Moulnupravir is just another modified nucleoside, like favipiravir, designed to fuck up viral replication. The problem is that you need to take high doses of this type of drug to substitute OG nucleosides in the cell and such drugs can cause mutagenic/teratogenic effects. Also, I have no idea why this is a "miracle drug" and other RNA replication disruptors are not, why you can start taking it 5 days after symptoms' onset and it's still gonna have an effect while other antivirals have failed there.
 
tulskij_tochnyj said:
It's not, just compare structures of molnupiravir and ivermectin, they are vastly different. Moulnupravir is just another modified nucleoside, like favipiravir, designed to fuck up viral replication. The problem is that you need to take high doses of this type of drug to substitute OG nucleosides in the cell and such drugs can cause mutagenic/teratogenic effects. Also, I have no idea why this is a "miracle drug" and other RNA replication disruptors are not, why you can start taking it 5 days after symptoms' onset and it's still gonna have an effect while other antivirals have failed there.
Click to expand...
Because it's new and can be sold at a higher price and it makes them look better.
They probably did the studies on other antivirals way late in the Coof progression when antivirals of course don't do shit anymore. Now they test it as an early treatment and hey, suddenly it works! Wow! Please buy our product now!
 
Whoever the hell is the guest on the People's Pundit claim they're having Spartacus of the Spartacus letter on. Wasn't that Drain Todger? lol
 
Vic Viper T301 said:
Former CNN contributor Marc Lamont Hill had a heart attack. Fully vaxxed.

He's claiming that it was caused by his Achilles surgery the previous week. Can anyone comment on how likely surgery on your ankle is to cause blood clots in your heart?
Click to expand...
I had a friend who turned her ankle once and it swelled up and went to the doctor to get it looked at, etc. A couple days later they found her unconscious in her apartment. She died shortly after they got her to the hospital with blood clots in her lungs that had originated in her ankle.
 
borsabil said:
https://youtube.com/watch?v=S4BpEr8gztU
I imagine this won't be up for long so if anyone feels like ripping it


Here's the Australian government's adverse reporting database for the Pfizer vaccine

Safety information & education

This section includes links to articles about the general safety of medicines and medical devices, including how the safety of products i
apps.tga.gov.au apps.tga.gov.au

201 reported deaths out of 25,000 cases

Astra Zeneca

Safety information & education

This section includes links to articles about the general safety of medicines and medical devices, including how the safety of products i
apps.tga.gov.au apps.tga.gov.au

Over 33000 reported cases with 324 deaths

Moderna

Safety information & education

This section includes links to articles about the general safety of medicines and medical devices, including how the safety of products i
apps.tga.gov.au apps.tga.gov.au

Although it was only rolled out a couple of weeks ago 3000 odd cases with 20 reported deaths

544 deaths from the jabs

Safety information & education

This section includes links to articles about the general safety of medicines and medical devices, including how the safety of products i
apps.tga.gov.au apps.tga.gov.au

Australia is the most rabidly pro-vaccine Covidian country on the planet. These numbers represent a vast underestimate of the actual risk profile but in comparison the flu vaccine had a total of 12 associated deaths.

More people have died from the vaccines in 2021 than with Covid.

I personally know of dozens of people who have suffered severe side effects from the vaccines including blood clots, terrible gastro symptoms, prolonged lethargy. lymph oedema, chronic pain, cardiac issues, high fever and so on. I only know of 1 person who's made a report to the the TGA. Most of them have sucked it up, taken sick leave and ridden it out. The few who've gone to their doctor have been told not to worry as it just the vaccine 'working',
Click to expand...
IMG_20211001_211123_904.jpg
 
It's a bit wierd reading some of the stuff in this thread. Apart from the odd old fogey wearing a mask, the pandemic is over in Britain. YMMV but I don't feel, see or hear about any restrictions to things, social distancing is largely out of the window, save for the strange seating arrangements in some hospitals, bus stations and banks.

To see australia going mental now, at the back end of 2021, and thousands of people losing their jobs in America, is very, very strange. Seeing those things in 2020 would have been bonkers, but more 'understandable'. Seeing it now is just...eh?
 
Hot Cup of Joe said:
It's a bit wierd reading some of the stuff in this thread. Apart from the odd old fogey wearing a mask, the pandemic is over in Britain. YMMV but I don't feel, see or hear about any restrictions to things, social distancing is largely out of the window, save for the strange seating arrangements in some hospitals, bus stations and banks.

To see australia going mental now, at the back end of 2021, and thousands of people losing their jobs in America, is very, very strange. Seeing those things in 2020 would have been bonkers, but more 'understandable'. Seeing it now is just...eh?
Click to expand...
That's isolated. Around where I am (within America) the only thing remaining of the pandemic are people complaining about the unvaxxed and the worry that they might soon do a national mandate.
 
Puff said:
That's isolated. Around where I am (within America) the only thing remaining of the pandemic are people complaining about the unvaxxed and the worry that they might soon do a national mandate.
Click to expand...
But we don't have any of that here. Johnson outright said the vaxport won't go ahead. Sturgeon (scottish leader) has been told by all of her cabinet and business leaders to bin it off because it won't work, but seems as her MO is "do the opposite of England" she's charging ahead with it. There were murmurs of a possible lockdown in October but that won't happen.

We just got battered with a very bad strain of cold/flu, so bad was it, that it was reported on by the BBC. But nobody said the word "lockdown", let alone "vax mandate". We're now just focusing on restocking and sorting out our staffing levels. Hell, the only mention of covid has been an off-the-cuff excuse for running out of fuel, even though it wasn't blamed as the main excuse.

So to see nurses, firefighters and soldiers laid off in America, and the aussies classing with the cops, is completely bloomin bonkers.
 
SSF2T Old User said:
Take your vaccine in pill form now

Article: https://longisland.news12.com/merck-says-experimental-pill-cuts-worst-effects-of-covid-19
Archive: https://archive.md/mPtJM
---------------------------------------------------
Merck says experimental pill cuts worst effects of COVID-19
Merck says experimental pill cuts worst effects of COVID-19.mp4
Merck & Co. said Friday that its experimental COVID-19 pill (Archive: https://archive.md/8osQN ) reduced hospitalizations and deaths by half in people recently infected with the coronavirus and that it would soon ask health officials in the U.S. and around the world to authorize its use.

If cleared, Merck's drug would be the first pill shown to treat COVID-19, a potentially major advance in efforts to fight the pandemic. All COVID-19 therapies now authorized in the U.S. require an IV or injection.
View attachment 2586720
Merck and its partner Ridgeback Biotherapeutics said early results showed patients who received the drug, called molnupiravir, within five days of COVID-19 symptoms had about half the rate of hospitalization and death as patients who received a dummy pill. The study tracked 775 adults with mild-to-moderate COVID-19 who were considered higher risk for severe disease due to health problems such as obesity, diabetes or heart disease.

Among patients taking molnupiravir, 7.3% were either hospitalized or died at the end of 30 days, compared with 14.1% of those getting the dummy pill. There were no deaths in the drug group after that time period compared with eight deaths in the placebo group, according to Merck. The results were released by the company and have not been peer reviewed. Merck said it plans to present them at a future medical meeting.

An independent group of medical experts monitoring the trial recommended stopping it early because the interim results were so strong. Company executives said they are in discussions with the Food and Drug Administration and plan submit the data for review in coming days.

“It exceeded what I thought the drug might be able to do in this clinical trial,” said Dr. Dean Li, vice president of Merck research. “When you see a 50% reduction in hospitalization or death that’s a substantial clinical impact.”

Side effects were reported by both groups in the Merck trial, but they were slightly more common among the group that received a dummy pill. The company did not specify the problems.

Earlier study results showed the drug did not benefit patients who were already hospitalized with severe disease.

The U.S. has approved one antiviral drug, remdesivir, specifically for COVID-19, and allowed emergency use of three antibody therapies that help the immune system fight the virus. But all the drugs have to given by IV or injection at hospitals or medical clinics, and supplies have been stretched by the latest surge of the delta variant.

Health experts including the top U.S. infectious disease expert Dr. Anthony Fauci have long called for a convenient pill that patients could take when COVID-19 symptoms first appear, much the way the decades-old flu medication Tamiflu helps fight influenza. Such medications are seen as key to controlling future waves of infection and reducing the impact of the pandemic.

Merck’s pill works by interfering with an enzyme the coronavirus uses to copy its genetic code and reproduce itself. It has shown similar activity against other viruses.

The U.S. government has committed to purchase 1.7 million doses of the drug if it is authorized by the FDA. Merck has said it can produce 10 million doses by the end of the year and has contracts with governments worldwide. The company has not announced prices.

Several other companies, including Pfizer and Roche, are studying similar drugs that could report results in the coming weeks and months.

Merck had planned to enroll more than 1,500 patients in its late-stage trial before the independent board stopped it early. The results reported Friday included patients enrolled across Latin America, Europe and Africa. Executives estimated about 10% of patients studied were from the U.S.
---------------------------------------------------
Click to expand...
I mean, I don't know if I see a problem with this guys. Shots are ouchies.
 
SSF2T Old User said:
The U.S. government has committed to purchase 1.7 million doses of the drug if it is authorized by the FDA. Merck has said it can produce 10 million doses by the end of the year and has contracts with governments worldwide. The company has not announced prices.
Click to expand...

www.reuters.com

Merck pill seen as 'huge advance,' raises hope of preventing COVID-19 deaths

An experimental antiviral pill developed by Merck & Co could halve the chances of dying or being hospitalized for those most at risk of contracting severe COVID-19, according to data that experts hailed as a potential breakthrough in how the virus is treated.
www.reuters.com www.reuters.com
The company has a U.S. government contract to supply 1.7 million courses of molnupiravir at a price of $700 per course.
Click to expand...

A little pricer than Ivermectin
 
Fanatical Pragmatist said:
"Everyone is forced to comply with the orders of not being forced to comply with anything"
Click to expand...
I love the random scare flashes of cops just standing around. What are they doing exactly? Going around giving people Australian style beatdowns for wearing masks? Raiding vaccination sites and crushing the vials of science juice?
 
I'm still hoping the Aussies rise up like the yellow vests. Remember that one boxer who had half the police running away because he could throw a decent punch?
 
Status
Not open for further replies.
Back
Top Bottom