UN Monkeypox Article Megathread

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Four more people have been diagnosed with monkeypox in the UK, bringing the total number of cases in the latest outbreak to seven.

All four new patients are gay or bisexual men who were infected in London and had no travel links to Africa, health chiefs have confirmed after MailOnline broke the news earlier today.

Two are known to each other but have no connection to any of the previous cases, in a sign the virus is spreading in the community for the first time.

Nurses and doctors are being advised to stay 'alert' to patients who present with a new rash.

Monkeypox is often mistaken for more common rash illnesses like chickenpox, measles, scabies and syphilis, which makes it difficult to diagnose early.

Dr Susan Hopkins, chief medical adviser at the UK Health Security Agency (UKHSA), said: 'This is rare and unusual.

'UKHSA is rapidly investigating the source of these infections because the evidence suggests that there may be transmission of the monkeypox virus in the community, spread by close contact.

'We are particularly urging men who are gay and bisexual to be aware of any unusual rashes or lesions and to contact a sexual health service without delay.'

All seven UK cases have tested positive for the West African strain of the virus, which is believed to be milder than other versions.
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Six of the seven cases were diagnosed in London while one is being treated at a specialist unit in Newcastle
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Monkeypox is a rare viral infection which causes unusual rashes or lesions (shown in a handout provided by the Centers for Disease Control and Prevention (CDC) in the US

Exactly how the new patients acquired the infection 'remains under urgent investigation', the UKHSA said.

The rare viral infection which kills up to one in ten of those infected but does not spread easily between people. It is transmitted via respiratory droplets during prolonged face-to-face contact or bodily fluids.

MailOnline has learned that at least one sexual health clinic in West London had started implementing tougher infection control measures this morning, including a one-metre social distancing rule in waiting rooms.

A source told MailOnline that some health teams were breaking ranks from national guidance and 'perhaps putting in measures locally'.

The UKHSA announced on May 7 that a person who had recently travelled to Nigeria had contracted the infection.

It was believed they contracted the illness in Nigeria, where monkeypox is endemic, before travelling to the UK.

Two more cases were announced on Saturday, in two individuals who lived in the same household but were not linked to the initial case.
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Nurses and doctors are being advised to stay 'alert' to patients who present with a new rash or scabby lesions (like above)
The rare tropical disease, which causes flu-like symptoms and blisters on the skin, is caused by a virus spread by monkeys, rats, squirrels and other small mammals.

A World Health Organization report last year suggested the natural R rate of the virus – the number of people each patient would infect if they lived normally while sick – is two.

But the real rate is likely much lower because 'distinctive symptoms greatly aid in its early detection and containment,' the team said, meaning it's easy to spot cases and isolate them.

Up to 10 per cent of people who become ill with monkeypox will die and most deaths from the virus occur in younger age groups, according to the WHO.

The first case of monkeypox in a human was recorded in 1970 in the Democratic Republic of the Congo and has since been detected in a number of central and wester African countries.

Most cases are reported in the DRC and Nigeria.

In 2003, the disease was detected in the US when an outbreak occurred following the importation of rodents from Africa.

The first cases were detected in the UK in 2018, when three people contracted the virus after a man travelled back from Nigeria including an NHS nurse who had been caring for a patient and blamed her PPE.

The incident meant more than 50 people were warned they had been exposed to the potentially deadly virus however no other cases were recorded from that outbreak.

A further case was detected in London in December 2019 and another two cases were detected in North Wales in 2021. All cases were thought to have been caught by travellers who had been to Nigeria.

A WHO report in 2020 explained that human-to-human transmission of the virus is rare and that the longest chain of cases appears to only have been six people before it ended.

The report said: 'The epidemic risk for humans is considered to be small.'
 
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Oh dear, the CDC really needs to cool it with the homophobic remarks. Very problematic; they need to be educated on what it means to be sex positive in current year plus nine.
 

New mpox outbreak raises alarm; WHO considers declaring international emergency​

A different clade of mpox than the previous outbreak is spilling out of the DRC.​

BETH MOLE - 8/7/2024

A deadly outbreak of mpox (previously called monkeypox) is spilling out of the Democratic Republic of the Congo, raising alarm among global health experts.

The DRC has reported more than 22,000 suspected cases since the start of 2023, including 1,200 suspected deaths, according to the US Centers for Disease Control and Prevention. A high proportion of the cases are in children younger than 15 years old.

On Wednesday, the CDC released a health advisory noting that although mpox is endemic to the DRC, the current outbreak is larger and more widespread than any outbreak the country has previously seen. The virus has also spilled over to several neighboring countries in recent months, including the Republic of the Congo, the Central African Republic, Burundi, Rwanda, and Uganda. The World Health Organization reported that cases have also been detected in Kenya.

Also on Wednesday, WHO Director-General Tedros Adhanom Ghebreyesus announced that he would convene an emergency committee as soon as possible to assess if the outbreak constitutes a public health emergency of international concern (PHEIC), the agency's highest level of alert.

Unlike the 2022–2023 international outbreak of mpox—which WHO declared a PHEIC in July 2022—the current outbreak is caused by a different clade of mpox; the previous outbreak was caused by clade II of the virus, while the current outbreak is caused by clade I, which causes more severe illness and death.

According to the CDC, symptoms of mpox include a rash that may be located on the hands, feet, chest, face, mouth, or near the genitals; fever; chills; swollen lymph nodes; fatigue; myalgia (muscle aches and backache); headache; and respiratory symptoms like sore throat, nasal congestion, and cough.

In the current outbreak, the spread seems to be occurring through well-known transmission routes, including contact with live or dead wild animals that carry the virus, household contact, and patient care. But, there's also evidence of spread through sexual contact, which is a first for clade I mpox.

For now, the CDC considers the risk to the US to be "very low," given that there are no direct flights between the US and the DRC or its neighboring countries. No cases of clade I mpox have been reported outside of central and eastern Africa so far. Still, in today's advisory, the CDC advised clinicians to consider mpox in patients with related symptoms who had traveled to the DRC or a nearby country in the past 21 days.

The mpox vaccines used in the previous outbreak are expected to be effective against both clades of the virus. In a separate announcement Wednesday, the US Agency for International Development (USAID) announced that it would provide $10 million to help the DRC respond to the outbreak, as well as 50,000 doses of mpox vaccine.
 
God to humanity: "cease your degeneracy."
*People continue to engage in sin and degeneracy*
God to humanity: "you asked for it."
*winds up a death plague that only affects a subset of the population that engages in said degeneracy*
Degens: "how could this happen to me?! Why does God allow meaningless pain and suffering to exist?!"
 
In the current outbreak, the spread seems to be occurring through well-known transmission routes, including contact with live or dead wild animals that carry the virus, household contact, and patient care. But, there's also evidence of spread through sexual contact, which is a first for clade I mpox
Unless something significant in the DRC has changed, a completely different clade of a virus becoming rapidly more virulent and also acquiring new routes of transmission, mirroring another clade in very quick succession, somewhat suggests cell mediated horizontal gene transfer has taken place.

I sure hope nobody's been injecting loads of people with mRNA instructions for making a virulence factor from something like a coronavirus!
 
The mpox vaccines used in the previous outbreak are expected to be effective against both clades of the virus
Well good luck with that. The OG smallpox vaccine was resisted in many areas, it has something like a 5.7% risk of myocarditis. It’s genuinely not a safe one at all.
The jynneos one that replaced it is supposed to be safer, but that doesn’t seem to have been established in human trials as far as I can see. The efficacy was established by using cell cultures and that’s about it.
I wouldn’t take either of them, personally.
 
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