UN Monkeypox Article Megathread

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Four more people have been diagnosed with monkeypox in the UK, bringing the total number of cases in the latest outbreak to seven.

All four new patients are gay or bisexual men who were infected in London and had no travel links to Africa, health chiefs have confirmed after MailOnline broke the news earlier today.

Two are known to each other but have no connection to any of the previous cases, in a sign the virus is spreading in the community for the first time.

Nurses and doctors are being advised to stay 'alert' to patients who present with a new rash.

Monkeypox is often mistaken for more common rash illnesses like chickenpox, measles, scabies and syphilis, which makes it difficult to diagnose early.

Dr Susan Hopkins, chief medical adviser at the UK Health Security Agency (UKHSA), said: 'This is rare and unusual.

'UKHSA is rapidly investigating the source of these infections because the evidence suggests that there may be transmission of the monkeypox virus in the community, spread by close contact.

'We are particularly urging men who are gay and bisexual to be aware of any unusual rashes or lesions and to contact a sexual health service without delay.'

All seven UK cases have tested positive for the West African strain of the virus, which is believed to be milder than other versions.
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Six of the seven cases were diagnosed in London while one is being treated at a specialist unit in Newcastle
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Monkeypox is a rare viral infection which causes unusual rashes or lesions (shown in a handout provided by the Centers for Disease Control and Prevention (CDC) in the US

Exactly how the new patients acquired the infection 'remains under urgent investigation', the UKHSA said.

The rare viral infection which kills up to one in ten of those infected but does not spread easily between people. It is transmitted via respiratory droplets during prolonged face-to-face contact or bodily fluids.

MailOnline has learned that at least one sexual health clinic in West London had started implementing tougher infection control measures this morning, including a one-metre social distancing rule in waiting rooms.

A source told MailOnline that some health teams were breaking ranks from national guidance and 'perhaps putting in measures locally'.

The UKHSA announced on May 7 that a person who had recently travelled to Nigeria had contracted the infection.

It was believed they contracted the illness in Nigeria, where monkeypox is endemic, before travelling to the UK.

Two more cases were announced on Saturday, in two individuals who lived in the same household but were not linked to the initial case.
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Nurses and doctors are being advised to stay 'alert' to patients who present with a new rash or scabby lesions (like above)
The rare tropical disease, which causes flu-like symptoms and blisters on the skin, is caused by a virus spread by monkeys, rats, squirrels and other small mammals.

A World Health Organization report last year suggested the natural R rate of the virus – the number of people each patient would infect if they lived normally while sick – is two.

But the real rate is likely much lower because 'distinctive symptoms greatly aid in its early detection and containment,' the team said, meaning it's easy to spot cases and isolate them.

Up to 10 per cent of people who become ill with monkeypox will die and most deaths from the virus occur in younger age groups, according to the WHO.

The first case of monkeypox in a human was recorded in 1970 in the Democratic Republic of the Congo and has since been detected in a number of central and wester African countries.

Most cases are reported in the DRC and Nigeria.

In 2003, the disease was detected in the US when an outbreak occurred following the importation of rodents from Africa.

The first cases were detected in the UK in 2018, when three people contracted the virus after a man travelled back from Nigeria including an NHS nurse who had been caring for a patient and blamed her PPE.

The incident meant more than 50 people were warned they had been exposed to the potentially deadly virus however no other cases were recorded from that outbreak.

A further case was detected in London in December 2019 and another two cases were detected in North Wales in 2021. All cases were thought to have been caught by travellers who had been to Nigeria.

A WHO report in 2020 explained that human-to-human transmission of the virus is rare and that the longest chain of cases appears to only have been six people before it ended.

The report said: 'The epidemic risk for humans is considered to be small.'
 
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Righto. Have had a quick look at the jynneos trials. The full protocol for the pivotal phase three is here: (there were 22 trials in total, this was the one that showed equivalence/non inferiority to the acam2000 shot.) https://www.clinicaltrials.gov/ProvidedDocs/53/NCT01913353/Prot_001.pdf
Archived here: https://archive.ph/wip/q4GGl
First things to note is that none of the approvals were based on the vaccine actually stopping people getting a disease in the wild. Smallpox is eradicated in the wild and the trials didn’t use exposure to monkeypox as a test at all. The efficacy measures of 85% seem to be based on survival rates of non human primates in one of the trial series.
The protocol included a group with exposure to the previous ACAm2000 vaccine which has a myocarditis rate of 5.7% (I’m kind of surprised that got past ethic review, I wouldn’t have passed it but whatever.)
The trial outcomes were all based around ‘take’ (having a lesion at the inoculation site) and other indirect measures like antibody titre and plaque work.
So what to make of this. Well ok, smallpox is a potential threat and a nasty one, and the live vaccines are dangerous, so yes there’s a rationale to develop a just-in-case . But look at how the narrative is turning now to ‘there’s a safe and effective vaccine.’ When actually, there isn’t. We don’t really know how safe it is becasue the trials were pretty small and the vaccine has a v v short use history and we don’t know how effective it is becasue not a single but of the data it was approved on was gained by exposing vaccinated people to the actual pathogen. Yet I will bet you there will be calls for mass vaccination and there will be ring vaccination.
 
we don’t know how effective it is
That's true, especially a few months after vaccination when the antibodies go down, but prior experience with orthopoxviruses show neutralizing antibodies to be protective against severe disease, and since the virus needs to go through the blood to get to the lesions on the skin, large portions of onward transmission. See intravenous immunoglobulin against Vaccinia (the vaccine virus) as a proof of protection. I'm worried about long-term protection however, as the further attenuation from the strains used in Dryvax and ACAM2000 almost certainly reduces the response of some types of T-cells, especially tissue-resident ones.
 
Only? That’s pretty high isn’t it? Almost 1/1000 rate. Were they actively looking for it? I.e were cardiac markers in the testing panels or was it reported via AE only?
I might go look up the trials. You’d take a vaccine that had a 1/1000 rate of myocarditis/pericarditis for a non lethal indication? I do t think I would.

This is another reason I was asking about photos - at least one of the media pics I’ve seen is of a hand with shingles. Now that might be the usual media ‘get me a hand with a rash for this story’ but I still haven’t seen a single current pic of a rash on a current patient that is definitely monkeypox, only library photos. This is the pic: https://archive.ph/J4m5K
I am going to go look up how these vaccines were tested becasue while they can have a phase three monkeypox trial there’s no more wild smallpox so they Muat have used some kind of proxy measure in vitro . I shall report back forthwith
The one in the Happenings thread looked for all the world like SJS which you can get from (a) any number of drugs you'd get if you tested positive for some mystery virus and went to the hospital and (b) just being immune compromised via aids, clotshot, etc.
 
When actually, there isn’t.
Look at this nazi chud with his "science" and statistics*
ALL VACCINES ARE SAFE MURDER

>I’m kind of surprised that got past ethic review
>pharmaceutical industry
>ethics
good joke bro most trials are a paperpushing joke unless THEY KNOW shit might cause "problems"
 
Well that is very good to hear, lets pray this doesn't mutate. Xpox is a horror from humanities past we "eradicated", a new airborne super strain would not be fun. Death rate is low as is infection rate this better die down. Sadly no lessons will be learned from this as always. Since not sticking your unprodected dick in a filthy pure bred african kneegrow is raycist. Or uh fucking random wild animals is normally a bad idea not just morally but biologically kek.

but then again its been ages since humanity has had to deal with a real pandemic plague. Modern medicine makes shit even stronger sadly isn't nature great. Just look at all the super bacteria raping India since those fuckers worship shit,sewage and filth. And north american doctors love shoving massive amounts antibiotics down your throat for no reason. The past decade is starting to show why this is a very very VERY V E R Y stupid idea.
We're due for something damning history repeats etc modern medican isn't some magical cure all. NORMALLY after/during really bad flues something worse pops up to take advantage of shit immune systems.
Monkeypox, cowpox, camelpox, chickenpox and horsepox are all part of the same family as smallpox but none are or were as deadly as smallpox. Infectious, yes, painful, yes, but leading to death? Only if you have other conditions. In the past, milkmaids were known for unusually clear skin as people who got smallpox had permanent scarring. Hence the term 'skin as smooth as a milkmaid'. Equestrian soldiers, farmers, page boys, anyone who worked with animals were spared from smallpox. This was noted in military journals when commanding officers noted their mounted infantry did not catch smallpox whereas those boys from the city did. Then Edward Jenner used a milkmaid and a cow named 'Blossom', and the modern vaccine was born.

Re: antibiotic resistance. It'll be back to the drawing board for that one, and 'natural' cures that, chemically, can stop the bacteria at its source, like certain species of wildflower and honey. Also gene sequencing and selective breeding.
 
A significant portion of all STDs would be rare or nonexistent if people would just stop being whores/whoremongers, but it seems like for whatever reason the "gay community" especially struggles in the horny department.

Not saying "no hand holding until marriage" just that it's not healthy physically or emotionally to have had like 25 different partners by the time you're 25.
If we started sterilizing whores and faggots this would have ended in its track . Side note in medieval periods there was outbursts of promiscuous behavior every few generations and ended very quick in a decade or two why because the stds will remove your promiscuous genes out of the genepool either by killing you or sterilizing you very fast. If you look at histories famous courtesans and hookers either they had only one child who died before reaching puberty or zero mention of children even if some of them were married right before they hit that wall or living ina period where was accepted men to have bastard children as long as they took care of them . There is also serious discrepancy in fertility for the same reasons between citys and villages on average city women fertility ended in their mid tweties compare that to peasant woman whose fertility ended in their mid thirties. In other words fuck the modern medicine.
 
Righto. Have had a quick look at the jynneos trials. The full protocol for the pivotal phase three is here: (there were 22 trials in total, this was the one that showed equivalence/non inferiority to the acam2000 shot.) https://www.clinicaltrials.gov/ProvidedDocs/53/NCT01913353/Prot_001.pdf
Archived here: https://archive.ph/wip/q4GGl
First things to note is that none of the approvals were based on the vaccine actually stopping people getting a disease in the wild. Smallpox is eradicated in the wild and the trials didn’t use exposure to monkeypox as a test at all. The efficacy measures of 85% seem to be based on survival rates of non human primates in one of the trial series.
The protocol included a group with exposure to the previous ACAm2000 vaccine which has a myocarditis rate of 5.7% (I’m kind of surprised that got past ethic review, I wouldn’t have passed it but whatever.)

Now you can see why I said that the Jynneos rate of cardiac adverse events being 8.5/10000 was a substantial improvement given the 5.7/100 rate with ACAM2000
 
ProMED Monkeypox update 10: https://promedmail.org/promed-post/?id=8703721 https://archive.ph/4qMLy There appears to be undetected spread in the US, because there are two genetically distinct viruses that get detected. Bavarian Nordic says the US is supposed to have immediate access to one million MVA-BN/Jynneos vaccine doses that are frozen somewhere, but the CDC apparently is either unaware of them or won't use them for some reason.
 

Monkeypox cases triple in Europe, WHO says, Africa concerned​

Associated Press (archive.ph)
By Maria Cheng and Farai Mutsaka
2022-07-01 18:50:36 GMT

LONDON (AP) — The World Health Organization’s Europe chief warned Friday that monkeypox cases in the region have tripled in the last two weeks and urged countries to do more to ensure the previously rare disease does not become entrenched on the continent.

And African health authorities said they are treating the expanding monkeypox outbreak as an emergency, calling on rich countries to share limited supplies of vaccines to avoid equity problems seen during the COVID-19 pandemic.

WHO Europe chief Dr. Hans Kluge said in a statement that increased efforts were needed despite the U.N. health agency’s decision last week that the escalating outbreak did not yet warrant being declared a global health emergency.

“Urgent and coordinated action is imperative if we are to turn a corner in the race to reverse the ongoing spread of this disease,” Kluge said.

To date, more than 5,000 monkeypox cases have been reported from 51 countries worldwide that don’t normally report the disease, according to the U.S. Centers for Disease Control and Prevention. Kluge said the number of infections in Europe represents about 90% of the global total, with 31 countries in the WHO’s European region having identified cases.

Kluge said data reported to the WHO show that 99% of cases have been in men — the majority in men that have sex with men. But he said there were now “small numbers” of cases among household contacts, including children. Most people reported symptoms including a rash, fever, fatigue, muscle pain, vomiting and chills.

Scientists warn anyone who is in close physical contact with someone who has monkeypox or their clothing or bedsheets is at risk of infection. Vulnerable populations like children and pregnant women are thought more likely to suffer severe disease.

About 10% of patients were hospitalized for treatment or to be isolated, and one person was admitted to an intensive care unit. No deaths have been reported.

Kluge said the problem of stigmatization in some countries might make some people wary of seeking health care and said the WHO was working with partners including organizers of gay pride events.

In the U.K., which has the biggest monkeypox outbreak beyond Africa, officials have noted the disease is spreading in “defined sexual networks of gay, bisexual, or men who have sex with men.” British health authorities said there were no signs suggesting sustained transmission beyond those populations.

A leading WHO adviser said in May that the spike in cases in Europe was likely tied to sexual activity by men at two rave parties in Spain and Belgium.

Ahead of gay pride events in the U.K. this weekend, London’s top public health doctor asked people with symptoms of monkeypox, like swollen glands or blisters, to stay home.

Nevertheless in Africa the WHO says that according to detailed data from Ghana monkeypox cases were almost evenly split between men and women, and no spread has been detected among men who have sex with men.

WHO Europe director Kluge also said the procurement of vaccines “must apply the principles of equity.”

The main vaccine being used against monkeypox was originally developed for smallpox and the European Medicines Agency said this week it was beginning to evaluate whether it should be authorized for monkeypox. The WHO has said supplies of the vaccine, made by Bavarian Nordic, are extremely limited.

Countries including the U.K. and Germany have already begun vaccinating people at high risk of monkeypox; the U.K. recently widened its immunization program to mostly gay and bisexual men who have multiple sexual partners and are thought to be most vulnerable.

Until May, monkeypox had never been known to cause large outbreaks beyond parts of central and west Africa, where it’s been sickening people for decades, is endemic in several countries and mostly causes limited outbreaks when it jumps to people from infected wild animals.

To date, there have been about 1,800 suspected monkeypox cases in Africa, including more than 70 deaths, but only 109 have been lab-confirmed. The lack of laboratory diagnosis and weak surveillance means many cases are going undetected.

“This particular outbreak for us means an emergency,” said Ahmed Ogwell, the acting director of the Africa Centers for Disease Control.

The WHO says monkeypox has spread to African countries where it hasn’t previously been seen, including South Africa, Ghana and Morocco. But more than 90% of the continent’s infections are in Congo and Nigeria, according to WHO Africa director, Dr. Moeti Matshidiso.

Vaccines have never been used to stop monkeypox outbreaks in Africa; officials have relied mostly on contact tracing and isolation.

The WHO noted that similar to the scramble last year for COVID-19 vaccines, countries with supplies of vaccines for monkeypox are not yet sharing them with Africa.

“We do not have any donations that have been offered to (poorer) countries,” said Fiona Braka, who heads the WHO emergency response team in Africa. “We know that those countries that have some stocks, they are mainly reserving them for their own populations.”

Matshidiso said the WHO was in talks with manufacturers and countries with stockpiles to see if they might be shared.

“We would like to see the global spotlight on monkeypox act as a catalyst to beat this disease once and for all in Africa,” she said Thursday.
 
Kluge said the problem of stigmatization in some countries might make some people wary of seeking health care and said the WHO was working with partners including organizers of gay pride events.
Now why would that be.
Kluge said data reported to the WHO show that 99% of cases have been in men — the majority in men that have sex with men.
In the U.K., which has the biggest monkeypox outbreak beyond Africa, officials have noted the disease is spreading in “defined sexual networks of gay, bisexual, or men who have sex with men.” (lol, wut?) British health authorities said there were no signs suggesting sustained transmission beyond those populations.
A leading WHO adviser said in May that the spike in cases in Europe was likely tied to sexual activity by men at two rave parties in Spain and Belgium.
Oh, I see. But I´m sure you have the perfect medical solution to this problem, you are the leading organization in the world on the subject.
WHO Europe director Kluge also said the procurement of vaccines “must apply the principles of equity.”
So we´re fucked, thanks for the heads up.
 
So basically the gays are once again spreading an exotic disease thanks to their obnoxious need to have raging promiscuous rawdog sex with randos.
In 20-30 years time they are all going to blame straight people for them catching another exotic STD (also from monkeys) because they were "stigmatized" or some shit.

History is repeating itself and we are watching in real time.
 
> monkey pox
> distribute monkey pox vaccine
> ???
> monkeys rise up while humans are distracted
> monkey pox becomes the monkey pax
> planet of the apes becomes real, with humans enslaved to work in their banana mines
 
> planet of the apes becomes real, with humans enslaved to work in their banana mines
Let's hope it's at least like the cooler 60's/70's version....

Damn that movie had the best ending monologue....
 
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