The Harwoods, Michael, Mary and little Clare, move from London to New York. There have been a spate of child disappearances in the Big Apple, and one day Clare goes missing. Some months later, the grieving, broken parents attend a funfair on Coney Island. During a sudden downpour they take shelter in a tent which turns out to be the entrance to a freak show. The star exhibit is the 'What-is-it?', a one-eyed, hideously deformed creature which the barker assures is female and aged no more than ten. On the boat home to England, Michael buys a newspaper. The lead story tells of a police raid on a laboratory in Harlem where the brilliant - albeit criminally insane - plastic surgeon, Sir John Trowbridge, has been performing abominable vivisections on children and animals which he then sells on to the freak shows ...