My in-laws live in MA-8, and they're aware of Flu, but that's about it. My father in law is insistent that Flu is a man ("That's a fuckin' guy..." first time he ever saw her on TV) and my mother in law agrees with him, going so far as to call Flu a "disgusting degenerate" for having his cock mangled. They're both retired, Kennedy era, Catholic Democrats, and in my experience people like them make up the majority of the electorate in MA-8, people Flu NEEDS to appeal to in order to have a snowball's chance in hell of winning that election.
My brother and sister in law also live in MA-8, and are far more "progressive" in terms of politics and which politicians they support. They would be the first to go door knocking for an openly gay or trans candidate. They're very aware of Flu, and look at her campaign as a scam for money/internet cred, and a joke.
So no, I don't think Flu's odds are very good this election cycle.