From what I've seen, Nanas generally love trolling the fuck out of their exceptional descendants.
Little Airhead: "Grandma, you'd understand these things if you'd read some of the groundbreaking research that's been done in gender theory. Also, bell hooks."
G-Ma: "I don't need to read anything to know you're acting like a little faggot."
Little Airhead: [breaking into tears] "This is why we can't even have a nice time at Thanksgiving! You're all so full of hate, and just want to erase me!!!" [runs out of the room to go sit outside on the front steps, alone]
G-Ma: "I think this calls for pie. Who wants pie?"