When Homer can't stop blaming himself for the loss of Apu, a weird string of events begins to unfold that could shake the very fabric of Springfield as we know it. The evil Psycho, Russell Cargill, under orders from a mysterious bureaucrat, is out for revenge against Homer and convinces the government to arrest him, while Kang is reprogrammed to incapacitate Grandpa Simpson and take his place. Meanwhile, Frink and his friends discover some weird signals emitting from space and Bart seems to be the key to it all. Finally, they discover that this force is Apu, whose spirits inhabits The Plot Hole, in which no life can be sustained...without horrific mishaps. In order to try and right his wrongs and find purpose within his life, Homer summons the denizens of Springfield for help. They steal equipment from Fink and transform the Homer's house into a galactic cruiser, christened the U.S.S. Exit Strategy, and blast off into space, bound for the moon of Rigel VII, where the Plot Hole is located. What follows is a series of hilarious hi-jinx and tear-jerking drama as the Simpsons square off against Russell, his forces, the jaded Kodos and the evil Executor, who kidnaps Lisa and makes her his apprentice. Marge enlists help from Rigellians to learn the ways of the Plot, as the Homer ventures alone into the Plot Hole and comes face to face with...his maker. Will our favorite Springfield denizens live long enough to get another season? Will Kang succeed in assimilating the crew before Grandpa Simpson can stop him? Will Homer give it all up or make the supreme sacrifice?