The upper right one is Chancellor Neighsayer. He's species-racist to the other species and wants Twilight's school to be for ponies only. Friendship stuff happens, blah blah, and he sees that he misjudged the other species and agrees that everyone can get along and hold hands and drink kombucha and that even someone in his position is still learning about what friendship means.
In a show about redemption and forgiveness, where one of the main-ish characters is a reformed villain, it's pretty wild to just go with the take of "nah we should just beat the shit out of people who don't agree with us" (Which could be anyone, because nazi, as we know, means people OOP doesn't like.)
Bottom right is Prince Blueblood, who's related to Celestia in some side media but he's a one off character from Season 1 IIRC. His whole thing is being a snob and awful suitor to Rarity. He's not really a political power or anything in Equestria, he literally exists for one episode and isn't taken very seriously. Also the message is really stupid given Equestria is a monarchy. I suppose they chose Blueblood for it because showing one of the female royalty of Equestria decapitated might be a bad look.
I'm not really sure about Lil Cheese in the top left. I think it's because he looks kind of effeminate because he has eyelashes but it's not super uncommon for younger male ponies to be illustrated with eyelashes and softer snouts.
I'm really not sure about bottom left with Cadence. No idea if it's some pro-choice thing or about HRT or what I'm not sure. It would be weird to do a pro-choice thing with her given she has a baby lol.
And eat the rich I don't really have much to comment on. That's the normallest one of the lot. OK horse sperg over sorry.