It's why everyone that talks about Ralph never dying cause of resilient white trash genes is retarded.
Both of his parents died relatively young, both of them plagued by chronic illness and addictions. Ralph himself already has more chronic health problems than both his parents combined, including heart attacks, the addictions of both his parents as well, half his body is bad: broken hips, bad knee, shattered skull and gimped arm. And, to top it off, at 39 he already looks older than either of his parents did when they died, which is actually impressive.
The only impressive things about Ralph is how quickly he's physically deteriorating.