Science New study links ‘good’ cholesterol with dementia

https://thehill.com/policy/healthcare/4238669-new-study-links-good-cholesterol-with-dementia/

https://archive.ph/h9Zp8

A study shows that so-called “good cholesterol” may not be as healthy as previously believed.
The study, published Wednesday in the journal Neurology, claims that high or low levels of high-density lipoprotein, or HDL, could increase dementia risk for older people.
Researchers tracked more than 180,000 California residents through health surveys for about two years starting between 2002 and 2007, then tracked the group using medical records for about nine years on average. The subjects are now an average of 70 years old.
“Previous studies on this topic have been inconclusive and this study is especially informative because of the large number of participants and long follow-up,” study author Maria Glymour said in a statement. “This information allowed us to study the links with dementia across the range of cholesterol levels and achieve precise estimates even for people with cholesterol levels that are quite high or quite low.”
During the course of the study, about 25,000 people developed dementia.
People with the highest levels of HDL cholesterol had a 15 percent higher rate of dementia compared to those in the middle group, the study found. Those with the lowest levels had a 7 percent higher rate of dementia compared to those in the middle group.
The recommended “healthy” HDL amount is 40 mg/dL in blood. Study subjects’ average was about 54 mg/dL.
The study also tracked LDL cholesterol, dubbed “bad cholesterol,” but found that it did not significantly impact dementia rates.
“The elevation in dementia risk with both high and low levels of HDL cholesterol was unexpected, but these increases are small, and their clinical significance is uncertain,” Glymour said. “In contrast, we found no association between LDL cholesterol and dementia risk in the overall study cohort. Our results add to evidence that HDL cholesterol has similarly complex associations with dementia as with heart disease and cancer.”
The study released Wednesday follows the results of another released in July which found that having cholesterol levels which fluctuate over time may also increase dementia risk. That study, also published in Neurology, found that people whose cholesterol levels fluctuate the most are at about 19 percent higher risk of dementia.

 

[Fascist Frederick]

Does the study take into account that fat fucks don't live long enough to get dementia?

 

[Equal Rights for Androids]

idk, the fact that you're getting dementia at both higher and lower than normal levels indicates that it's not conclusive enough to link dementia to HDL. It could be correlated to other health issues and the HDL levels are just a symptom of whatever else they're doing in their lives at the time. Dementia can be caused by so many things that linking this to it... there's not strong enough evidence. If the statistics were 30+% higher then I would be saying yes, there is a clear link. But as it stands, only 13.8% of their population size got dementia. That could be due to bad diet, lack of exercise, genetics, low social interaction... Too many factors to determine that HDL is a link.

Just another paper to line researcher's names with fluff pieces.

 

[Watcher]

Considering dementia rates are increasing worldwide while also coinciding with increased "bad cholesterol" diets I'd say there isn't a correlation. The best evidence I've seen for increased Dementia/Alzheimer's rates is lack of sleep or genetics.

 

[Penis Drager 2.0]

idk, the fact that you're getting dementia at both higher and lower than normal levels indicates that it's not conclusive enough to link dementia to HDL. It could be correlated to other health issues and the HDL levels are just a symptom of whatever else they're doing in their lives at the time. Dementia can be caused by so many things that linking this to it... there's not strong enough evidence. If the statistics were 30+% higher then I would be saying yes, there is a clear link. But as it stands, only 13.8% of their population size got dementia. That could be due to bad diet, lack of exercise, genetics, low social interaction... Too many factors to determine that HDL is a link.

Just another paper to line researcher's names with fluff pieces.

Once it was discovered that the Amyloid study was a literal fraud, people have been clamoring to make a name for themselves and discover what's actually causing it. Weak studies like this are going to abound.

 

[Zbk3VmLfujjzjxBd43tL]

7 percent higher is within the margin of error. If your diet is full of cholesterol, your arteries are probably fucked up enough that it won't be the dementia that kills you.

 

[Otterly]

Considering dementia rates are increasing worldwide while also coinciding with increased "bad cholesterol" diets I'd say there isn't a correlation. The best evidence I've seen for increased Dementia/Alzheimer's rates is lack of sleep or genetics.

We need cholesterol - it’s a precursor for a lot of vital things. Levels are very linked to genetics.
Dementia is an end stage of multiple processes. Inflammation, vascular events, possible disease reaction etc.
This will be used to push more statins on people but I also don’t think that’s the right thing to do.

 

[Fruttasecca]

I think a big, completely underrepresented factor of current year insanity is the shitty nutrition people have.
Most importantly people dont eat enough animal fats so their brains dont work properly, its not politics, its not "socio economic factors", its not the "zeitgeist" its literary just peoples brains not working properly.
Drop the carbs, buy read meat from the butcher, eat more organs and replace the butter/olive oil with lard.

 

[New Fag]

Cause, like, when you start learning about healthcare food, everything gives you cancer, everything will make you ill, everything is bad for you, and you have to point it all out to everyone all the time.

 

[Blasterman]

I think a big, completely underrepresented factor of current year insanity is the shitty nutrition people have.
Most importantly people dont eat enough animal fats so their brains dont work properly, its not politics, its not "socio economic factors", its not the "zeitgeist" its literary just peoples brains not working properly.
Drop the carbs, buy read meat from the butcher, eat more organs and replace the butter/olive oil with lard.

This. The reason people are dying en masse from "bad diets" is because they use overly-processed shit. Optimal diet should be low on carbs (so little to no fruit and more emphasis on vegetables as a source of vitamin), moderate on fat and medium-to-high on protein (that means more meats of various kinds, more milk, more eggs). Avoid bread unless keto/gluten free. Occasional pasta or something like that is okay as long as it's kept at that: occasional. Avoid processed and canned shit. If possible, buy straight from the farmers and avoid supermarkets 'cause not even God knows what the hell they put in there anymore.

 

[ZazietheBeast]

Sometimes I wonder if these studies are in reality a giant smokescreen in general for a bad diet and a crappy lifestyle encouraged by (((mass media))).

Sugar and HFCS is insanely bad for you and will give you beetus which fucks up all sorts of organs. Eyes included. Being turbo-fat will lead to early death and heavy on complications, blood pressure meds just mitigate that but not eliminate the problem that comes with being fat. Eating processed food 24-7 will fuck you up. Anything deep fried in corn oil will fuck you up. 3 meals a day is a total meme. Fasting is king. Pay no attention to big pharma who is purposely keeping medical technology outdated.

This. The reason people are dying en masse from "bad diets" is because they use overly-processed shit. Optimal diet should be low on carbs (so little to no fruit and more emphasis on vegetables as a source of vitamin), moderate on fat and medium-to-high on protein (that means more meats of various kinds, more milk, more eggs). Avoid bread unless keto/gluten free. Occasional pasta or something like that is okay as long as it's kept at that: occasional. Avoid processed and canned shit. If possible, buy straight from the farmers and avoid supermarkets 'cause not even God knows what the hell they put in there anymore.

Fun fact, in the infamous 'eat ze bugs' video by the WEF, they mentioned meat being a once a week special treat. Never mind the fact that you need meat to function properly. In fact, anyone who works a blue collar physical labor job is gonna need meat to function correctly. Build the muscle, maintain organs. Their plan is effectively societal suicide.

 

[SpergioLeonne]

People are going to die no matter what. There’s too much Karen-ing out about diet and not enough about physical activity.

Take a reputable vitamin, don’t catastrophically exceed your calorie requirements, and take a fucking walk once in a while. Your body has an amazing ability to sort itself out as long as you don’t let it atrophy

 

[Big moth tiddies]

I don't believe studies or even "science" anymore given the events of the last four years.

I still remember one of the studies thoroughly destroying my belief in this shit being the WHO saying red meat causes cancer, and also diet coke causes diabetes.

By the way, their justification for diet coke causing diabetes was "Hurr durr, we did a poll and people who drink diet coke are more likely to have diabetes!"

No shit, retard. That's why they're drinking it.

Sometimes I wonder if these studies are in reality a giant smokescreen in general for a bad diet and a crappy lifestyle encouraged by (((mass media))).

It's well documented that companies fund studies about their own products, and if they don't get the results they want, they bury it. I know for sure nestle and coke have both done it. Globohomo has covered for them now though and if you search for it in general, all you'll get is "Oh noes! Oil companies knew about climate change 40 heckin years ago!"

Sometimes studies are just bullshit so the fuckers doing it can make a name for themselves. Doesn't help they can't get funding unless they're sucking some kind of social or corporate dick either.

 

[cactus]

This. The reason people are dying en masse from "bad diets" is because they use overly-processed shit. Optimal diet should be low on carbs (so little to no fruit and more emphasis on vegetables as a source of vitamin), moderate on fat and medium-to-high on protein (that means more meats of various kinds, more milk, more eggs). Avoid bread unless keto/gluten free. Occasional pasta or something like that is okay as long as it's kept at that: occasional. Avoid processed and canned shit. If possible, buy straight from the farmers and avoid supermarkets 'cause not even God knows what the hell they put in there anymore.

I don't think multigrain bread full of fiber is that bad. Fruit is also full of fiber and fiber offsets the carbs in these foods. Also fruit is natural and full of vitamins as well.

I don't see how cholesterol would affect someone getting dementia, since it clogs up the arteries, unless there's some blood flow issues, but that hasn't been proven either.

 

[I (Don't) Have A Gun]

Just another paper to line researcher's names with fluff pieces.

To take a more charitable view it's just another data point. As much as we'd like every study to be conclusive (and I have no doubt that plenty of people will treat this as conclusive...) the real value of research comes comes in when a meta-analysis is done when all the individual studies with their often varying results are grouped together to see if a larger pattern can be found.

I still remember one of the studies thoroughly destroying my belief in this shit being the WHO saying red meat causes cancer, and also diet coke causes diabetes.

So diabetes is the result of insulin tolerance building up over time (insulin lower blood sugar). A large sugary diet causes your body to release more insulin (obviously because your body doesn't like too much glucose) and then your cells become less reactive to insulin over time and your body is unable to properly regulate the blood sugar levels.
They've done very simple tests: give people artificial sweeteners and test their insulin levels. The finds are that artificial sweeteners still increases insulin levels. So yeah there is actually a link, it's a pretty straight forward A to B. Although since you're body is unable to process artificial sweeteners you're not going to get fat from it, and i do believe the amount of insulin is lower. So there's still health benefit overall but you can easily see the A to B of how they came to that conclusion.

 

[Mordecai "3 Finger" Brown]

If your diet is full of cholesterol, your arteries are probably fucked up enough that it won't be the dementia that kills you.

There's a vascular subtype of dementia which mimics Alzheimer's but actually has some objective evidence that can be picked up by neuroimaging.

So you are correct that many people with cardiovascular disease won't even get there. But the flip side is that those that do often have brains looking like Swiss cheese due to mini-strokes.

This will be used to push more statins on people but I also don’t think that’s the right thing to do.

When we used to calculate Framingham Risk scores on charts by hand, the scoring system made it obvious that advancing age was weighted so heavily that none of the other factors like smoking or diabetes or cholesterol indices actually mattered.

Essentially a person of a certain age with zero risk factors would eventually be recommended statins simply because they'd crossed a threshold and scored high enough.

I once did some reading to figure out when it was appropriate to stop statins in the elderly or at what age it didn't make sense anymore to initiate them.

Essentially, the answer to both was that anyone who's life expectancy was greater than 2 years was argued to benefit from statins. And the way they defined life expectancy of two years was anyone not actively dying of something - cancer, etc.

They argued via actuarial tables that even centenarians that weren't specifically palliative should stay on statins because their life expectancy still exceeded two years.

 

[SuperShibuyaFighter]

Dementia took my grandfather. I will never forgive global homo for it.

If we weren't so obsessed with troons and funding diversity quotas maybe we'd have a cure or at least a better way to treat dementia by now. Plus his dementia accelerated coincidentally after taking the vaccine.

 

[Big moth tiddies]

They've done very simple tests: give people artificial sweeteners and test their insulin levels. The finds are that artificial sweeteners still increases insulin levels. So yeah there is actually a link, it's a pretty straight forward A to B. Although since you're body is unable to process artificial sweeteners you're not going to get fat from it, and i do believe the amount of insulin is lower. So there's still health benefit overall but you can easily see the A to B of how they came to that conclusion.

You're overthinking this man.
People who have diabetes avoid sugar, so they're more likely to choose sugar free drinks.
That's it, and the study I was referencing didn't mention any of the shit you just did. It was simply, "we polled this many people, and we found the people who were diabetic were more likely to drink diet coke."

You're going so far into being smart that you flip the counter into stupidity.

 

[Iron Jaguar]

How can they tell the difference between Californians with dementia and any other Californians?

 

[WonderWino]

We need cholesterol - it’s a precursor for a lot of vital things. Levels are very linked to genetics.
Dementia is an end stage of multiple processes. Inflammation, vascular events, possible disease reaction etc.
This will be used to push more statins on people but I also don’t think that’s the right thing to do.

We do need cholesterol, but we don't need it at all in our diet. Almost all animals synthesize their own, humans included