Oh don't get me wrong, I think putting trannies into literally any setting is stupid as fuck because it makes zero sense to be "trans" in a world where you can go full chrome like Lizzy Wizzy, or in a world where you can drink a potion to turn you into your desired sex, but as far as forced trans points go Claire is one of the less offensive examples because there's an actually interesting character to be discovered should you care to, yet it is a character you can ignore entirely and go through the entire game bar Claire's specific mission list without ever noticing that she is in fact voiced by a dude and you won't ever see the trans flag on the back of the Beast either.
Exploring Claire's story did break my immersion as she explained how her transition was True and Honest in the year of 2077 where you have murderhobo gangbangers with so many implants that they go cyberpsycho, yet Claire's family struggled with accepting her and all of that nonsense. I still much prefer a non-Mary Sue trans character that is completely optional, but to be clear it is still a turd in my delicious sandwich and I would much rather CDPR didn't put the turd in my meal.