This is actually legitimately more interesting than with Pokemon
I mean Twitch plays Pokemon was semi-interesting in that it was inevitable they'd beat the game. It was just a question of how long. But with fish trying to play such a game it'd take forever just to leave Pallet town.
With Street fighter though it's a much simpler game by comparison and the added effect of multiplayer makes for more amusing situations like both characters jumping in the air constantly. Plus because it's fish and no time limit it adds a little to the suspense.
Supposedly the creator is also planning for special move macros to be implemented somewhere in the fishtank. So that should make a fight more dynamic.
They're also conceptualizing Twitch vs Fish which sounds like the best idea I could have ever heard.