Science Bird Flu, Explained - We explore whether you should be worried.

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Bird Flu, Explained
The New York Times (archive.ph)
By David Leonhardt
2024-12-04 11:57:28GMT

birdflu01.jpg
Credit...Bryan Anselm for The New York Times

By now, you’ve probably seen some alarming headlines about bird flu, and you may be wondering how worried you should be. I understand the uncertainty.

On the one hand, we have all spent decades hearing alarming stories about strange viruses — like MERS, Ebola, dengue and Zika — most of which don’t end up having a big effect on the U.S. On the other hand, one of those recent viruses turned into the life-altering Covid pandemic.

In today’s newsletter, I want to help you make sense of bird flu, using four questions.

Making sense of H5N1​

1. What is bird flu?
It’s an influenza virus officially known as H5N1 (and sometimes called avian flu). It has been circulating for decades, and it attracted global attention in the late 1990s after an outbreak among chickens in southern China.

That outbreak was especially worrisome because it included the first documented human cases of the virus. At least 18 people were infected, six of whom died.

2. Why the recent concerns?
The virus has recently expanded in two ways: across regions and across species. Rather than being concentrated in Asia, bird flu has moved across much of the planet. And it has infected a wider variety of animals, including mammals. (This Times story explains.) Dairy cows in many parts of the United States have tested positive.

The number of human infections is also growing, as this chart by my colleague Ashley Wu shows:
birdflu01.png
Credit...Source: C.D.C. | Data is through Oct. 2024. | By The New York Times

Most concerning, at least four people have tested positive without evidently having had contact with a sick animal. One is them is a teenager in British Columbia who has been in critical condition. These infections raise the possibility that the virus can move from one human being to another, rather than only from an animal to a person. Human-to-human transmission can lead to much more rapid spread of a disease.
“I’m more worried about bird flu than I have been for a really long time,” Jennifer Nuzzo, director of the Pandemic Center at the Brown University School of Public Health, told me.

3. What are the reasons to be hopeful?
There are a few. First, it’s not yet clear whether those four recent cases stemmed from human-to-human transmission. Even if they did, such transmission might remain rare, involving extremely high levels of exposure to the virus. “Right now, H5N1 does not spread easily between people,” said Caitlin Rivers, an epidemiologist at the Johns Hopkins Center for Health Security.

Second, H5N1 seems to have become less severe in human beings recently. The reasons aren’t clear, Nuzzo says, but one possibility is that a different flu that emerged in 2009 — H1N1 — may confer some immunity for H5N1. Millions of people have since had H1N1.

As my colleague Apoorva Mandavilli says, “Very few people known to be infected with bird flu in the United States have become seriously ill, and none have died.” Still, she notes that viruses evolve, often in ways that lead to more infections. And the upcoming winter could give bird flu more opportunities to mix with seasonal flu and mutate. If bird flu were to spread widely, even a low fatality rate could mean tens of thousands of deaths in the U.S.

4. How can the U.S. reduce the risks?

More testing — of birds, cows and farmworkers — would help. “We know very, very little about how far this virus has spread and how many people and animals have been infected,” Apoorva said. Testing could allow farms to isolate infected animals and people.

birdflu02.jpg
In Wisconsin. Credit...Jim Vondruska/Reuters

What about a vaccine? A vaccine for bird flu exists, but the supply is modest. Nuzzo believes the government should help expand production and make the vaccine available to farmworkers who want to receive it. More research on the vaccines also seems important, especially if the virus is evolving.

The bottom line​

Rivers, the Johns Hopkins epidemiologist, recently published a book on preventing outbreaks called “Crisis Averted.” In it, she argues that one of the most effective public health strategies is honesty: Experts should level with people, rather than telling selective truths intended to shape behavior in paternalistic ways (as happened during Covid).

When I spoke with Rivers this week, I asked for some truth telling about bird flu. “As an epidemiologist, I’m worried,” she said. “I’m not worried as a mom or a member of my community. It’s not a threat that is imminent.”

But H5N1 bears watching. It is changing and spreading in uncertain ways, and it already presents a threat to many animals and to people who work closely with them.

For more: In Times Opinion, Zeynep Tufekci argues that President Biden should be more aggressive about fighting bird flu before leaving office.
 
The opinion article By Zapper Turkey mentioned in the OP:

A Bird Flu Pandemic Would Be One of the Most Foreseeable Catastrophes in History
The New York Times (archive.ph)
By Zeynep Tufekci
2024-11-29 22:14:04GMT
birdflu00.jpg
Credit...Felix Decombat

Almost five years after Covid blew into our lives, the main thing standing between us and the next global pandemic is luck. And with the advent of flu season, that luck may well be running out.

The H5N1 avian flu, having mutated its way across species, is raging out of control among the nation’s cattle, infecting roughly a third of the dairy herds in California alone. Farmworkers have so far avoided tragedy, as the virus has not yet acquired the genetic tools to spread among humans. But seasonal flu will vastly increase the chances of that outcome. As the colder weather drives us all indoors to our poorly ventilated houses and workplaces, we will be undertaking an extraordinary gamble that the nation is in no way prepared for.

All that would be more than bad enough, but we face these threats gravely hobbled by the Biden administration’s failure — one might even say refusal — to respond adequately to this disease or to prepare us for viral outbreaks that may follow. And the United States just registered its first known case of an exceptionally severe strain of mpox.

As bad as the Biden administration has been on pandemic prevention, of course, it’s about to be replaced by something far worse. Robert F. Kennedy Jr., Donald Trump’s pick to lead the nation’s vast public health agency, has already stated he would not prioritize research or vaccine distribution were we to face another pandemic. Kennedy may even be hastening its arrival through his advocacy for raw milk, which can carry high levels of the H5N1 virus and is considered a possible vector for its transmission.

We might be fine. Viruses don’t always manage to adapt to new species, despite all the opportunities. But if there is a bird flu pandemic soon, it will be among the most foreseeable catastrophes in history.

Devastating influenza pandemics arise throughout the ages because the virus is always looking for a way in, shape shifting to jump among species in ever novel forms. Flu viruses have a special trick: If two different types infect the same host — a farmworker with regular flu who also gets H5N1 from a cow — they can swap whole segments of their RNA, potentially creating an entirely new and deadly virus that has the ability to spread among humans. It’s likely that the 1918 influenza pandemic, for example, started as a flu virus of avian origin that passed through a pig in eastern Kansas. From there it likely infected its first human victim before circling the globe on a deadly journey that killed more people than World War I.

And that’s why it’s such a tragedy that the Biden administration didn’t — or couldn’t — do everything necessary to snuff out the U.S. dairy cattle infection when the outbreak was smaller and easier to address.

Last winter, when cattle in the Texas Panhandle started getting sick, it wasn’t the established public health channels that figured it out. It took the efforts of a single veterinarian, Dr. Barb Petersen, who had the foresight and the determination to get some samples and send them to a friend at Iowa State University who could test for bird flu.

The results, and what has since come into view about the speed of the spread, should have set off every alarm imaginable.

Even now, however, there is little routine testing of farmworkers or close contact tracing for those who fall ill. We still have way too little information on how the virus spreads among cows. Its genetic sequences are being published very late, if at all, and without the kind of data necessary to understand and trace the outbreak. And the way the virus is spreading from herd to herd makes it clear that infected cows are still being moved around rather than isolated.

One recent study of 115 farmworkers found that about 7 percent of them showed signs of a recent, undetected H5N1 infection. They’d been going about their lives — visiting markets, churches, other homes — while harboring the potential seed of a new pandemic.

Last year, when a milder strain of mpox first reached the United States, we saw a glimpse of what an effective public health response looks like. The White House appointed Robert Fenton, an experienced FEMA administrator, and Demetre Daskalakis, a high-ranking official from the Centers for Disease Control and Prevention, to head the response. Daskalakis has extensive experience combating sexually transmitted diseases that disproportionately affect the gay community. While some right-wing critics obsessed over his tattoos, the pair led a smart campaign to vaccinate and educate, effectively ending the outbreak.

For the H5N1 outbreak among dairy cattle, however, the C.D.C. has limited powers. This show is run by the United States Department of Agriculture, led under Biden by Tom Vilsack, an alumnus of the Obama administration who in between those two postings took a turn in a powerful dairy industry position. The agency had already been weakened by attacks on its scientific side during the first Trump term. This time around, at a critical juncture, it has put a higher value on the short-term profits of the powerful dairy farming industry than on the health of billions of people.

Meanwhile, worrying signs keep cropping up.

Just a few weeks ago, a pig in a backyard farm in Oregon was found to have bird flu. It seems to have gotten it from sick poultry on the same farm. Pigs cause extra worry because they are considered to be ideal mixing vessels for various animal flu viruses to adapt and spread among humans. Last week, the virus was found in a flock of ducks at a pet fair in Hawaii, the one state that hadn’t previously found a case — probably transmitted by wild birds, which continue to spread the illness far and wide. Of the 34 individuals who were exposed at that pet fair, including 13 who had respiratory symptoms, all were offered voluntary testing. Five declined.

A teenager in Canada was infected, and the virus showed some key mutations that bring it closer to adapting to spread among humans. This outbreak has so far been mostly mild in humans, but historically it has been deadly, and further mutations could make it so again. That Canadian is in critical condition, unable to breathe independently.

There’s also an infected child in California who was not known to have come into contact with any sick animals at all, which raises the terrifying possibility that he got it from another human being. And the virus levels in the wastewater in several states keep spiking.

It’s certainly true that taking on powerful industrial farming interests would have created political headaches for the Biden administration. Perhaps it’s even true that if it had done the right thing and acted aggressively to stomp out the cattle outbreak, it could have cost the Democrats the presidency, the House and the Sen — —

Well, never mind.

I can only hope we continue to get lucky. We don’t have much else going for us.

We do have one thing. Biden is president for another seven weeks or so. It’s not too late for him to give the nation a parting gift. He could start taking these risks as seriously as he should have when the cattle infections were discovered. We could get serious about mandatory testing of cows, milk and farmworkers and about isolating infected cattle herds — as we already do for birds and pigs. We could speed up development of the vaccine that’s already in the works for cows and expedite all precautions for humans, too. It’s true that one doesn’t get proper, timely credit for disasters averted. But history will, eventually, deliver its verdict.

Zeynep Tufekci (@zeynep) is a professor of sociology and public affairs at Princeton University, the author of “Twitter and Tear Gas: The Power and Fragility of Networked Protest” and a New York Times Opinion columnist. @zeynepFacebook
 
My general rule with such things is if the media is trying to make people afraid, it's a tactic and I ignore it. If the media is trying to keep people calm, it's time to panic.
 
My general rule with such things is if the media is trying to make people afraid, it's a tactic and I ignore it. If the media is trying to keep people calm, it's time to panic.
I asked people during Covid; if the media hadn’t told you about Covid, and you’d never heard of it, going purely on your experience of people around you getting poorly, would you have been freaked out?

For the people gracious enough to actually think about the question, the answer was ‘I’d think there was a nasty flu going around, like that year when …’
If there’s ever a deadly plague going round, you’ll know about it because people will be dropping dead around you. Women in war zones during epidemics walk hundred of km with children strapped to their backs to get vaccinations against measles etc, because they can SEE what’s going on. when we live in vast cities we lose this direct feedback, we could be told people are dropping dead and how would we know? In a little village you can see two frail elders copped it, the kids have had a sniffle and Susan from up the road had a terrible cough but is on the mend. Much harder to lie to people.

Flu IS a pandemic threat. It will at some point spit out another spicy one for us and we will again go through the process of a year or so of nasty flu, and then it will weaken dramatically. Unlike previous very severe outbreaks like 1917 we now have antibiotics which don’t help against flu but do help for the big killers like bacterial pneumonia which piggyback on it. if there is a problem, you will know about it from simply looking around you.
What DOES worry me is not the flu, but the things the flu will be used to justify
 
This is a good point: if they had just been honest during COVID…
Wouldn't have made as much money on vaccines, though.

Hardly any in fact given that they were only approved under emergency legislation granted because there were no other treatments. If they'd been honest about the value of ivermectin as a prophylactic, or the lack of proven effectiveness of their own, it would not have been granted.
 
Wouldn't have made as much money on vaccines, though.

Hardly any in fact given that they were only approved under emergency legislation granted because there were no other treatments. If they'd been honest about the value of ivermectin as a prophylactic, or the lack of proven effectiveness of their own, it would not have been granted.
The vaccine thing angers me because they rushed them to market without doing due diligence in testing (which by the way, happened under Trump’s orders) and that has lead to even worse outcomes.

I’m not against vaccines in principle, but the COVID vaccines were rushed out too soon and too fast; I’ve seen first hand the negative side effects in people who got one shot early on and realized their mistake when it was too late and never got any boosters after that. I’d even argue that was worse than the virus when it was really potent in killing the compromised.

The medical community lost all credibility by obfuscating everything, silencing those who spoke out about the dangers of a fast rollout without thorough testing, and then trying DARVO tactics to deflect blame. Is it any wonder why people haven’t taken bird flu or mpox seriously? The medical/scientific communities have no one to blame but themselves.
 
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