If you just mean direct synonyms like "jogger" then maybe, but for more complex meanings I think there's a difference between words like "nigger", "tranny", "faggot" which more or less have PC synonyms and are just banned as a power move, and words like "simp", "incel", and "virgin" which are harder to succinctly replace. I think the former lose a lot of their power (both edgy appeal and conditioned revulsion) through simple substitution, look at all the digital ink spilled over "hard R".
Yes, words acquire nuance that would be lost by synonyms, but some words would lose more than others.
Also "simp" should stand for "simpering" not "simpleton" jfc
If I want to learn more about resorting cants is there a better term to look up, or a source?