Yet another study shows hydroxychloroquine doesn't work against Covid-19 - CNN really wants this drug to not work to own Orange Badman

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A new study -- the largest of its kind -- shows that hydroxychloroquine, the drug touted by President Trump, does not work against Covid-19 and could cause heart problems.

The study was published Monday in the Journal of the American Medical Association. It follows a study published Thursday in the New England Journal of Medicine that also showed the drug doesn't fight the virus.

Even before these reports were published, the US Food and Drug Administration and the National Institutes of Health issued warnings about using the drugs for coronavirus patients.

In the most recent study, researchers at the University at Albany looked at 1,438 patients with coronavirus who were admitted to 25 New York City area hospitals. After statistical adjustments, the death rate for patients taking hydroxychloroquine was similar to those who did not take the drug. The death rate for those taking hydroxychloroquine plus the antibiotic azithromycin, was also similar.

However, the patients who took the drug combination were more than twice as likely to suffer cardiac arrest during the course of the study. Heart issues are a known side effect of hydroxychloroquine.

"The big takeaway for me from this study is that it's very consistent with the FDA and NIH guidelines that came out in April," said one of the study's senior authors, David Holtgrave, dean of the School of Public Health at the University at Albany. "When deciding on public health interventions and treatments for Covid-19 or any other disease, it's really important to follow the data and follow the science and make sure decisions are being made on the highest quality data possible."

This study likely won't be the last word on the drugs. Researchers at the University of Washington, New York University and other centers are still testing the drug in patients.

In the clinical trials, coronavirus patients are randomly assigned to take the drugs or to take placebos, which have no effect, and then the death rates between the two groups will compared. These types of studies are considered the most reliable.


Trump's enthusiasm for hydroxychloroquine
Starting in mid-March, President Trump became a frequent cheerleader for hydroxychloroquine, used to treat malaria, lupus and other diseases and the antibiotic azithromycin, often sold under the brand name Zithromax, or as a"Z-pack."

He promoted the drugs nearly 50 times, despite pleas from scientists to let studies decide if the treatment worked or not.

"HYDROXYCHLOROQUINE & AZITHROMYCIN, taken together, have a real chance to be one of the biggest game changers in the history of medicine," Trump tweeted on March 21.

Fox News frequently echoed Trump, but both the network and the president quieted down about the drugs once studies started showing they didn't work and possibly could hurt.

No difference in death rates
Trump's enthusiasm for the drugs was based on a French study of 20 patients in March that showed the drugs might work against the virus. That study was criticized for poor methodology, with experts calling it "pathetic" and "a complete failure."

The medical society that published that study later said the study "does not meet the Society's expected standard."

But the study was enough to excite Trump, and enough to excite doctors, who were free to prescribe the drugs because they're both already on the market to treat patients with other illnesses.

The latest study in the Journal of the American Medical Association looked at the medical records of 18% of all coronavirus patients hospitalized in the New York City area from March 15 to March 28.

In this group, doctors prescribed both drugs to 735 patients, just hydroxychloroquine to 271 patients, just azithromycin to 211 patients and neither drug to 221 patients.

They found that those taking hydroxychloroquine, either alone or with the antibiotic, were sicker than other patients to begin with and as time went on had a higher death rate. However, once the researchers statistically adjusted for the fact that the patients who took the drugs were sicker to start with, there was no statistical significance between the two death rates.

Overall, the patients had a 20% death rate.

The patients in the study were in the hospital, and other research teams are studying whether hydroxychloroquine can prevent coronavirus infection or slow it down in the beginning stages of the disease.

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However, once the researchers statistically adjusted for the fact that the patients who took the drugs were sicker to start with, there was no statistical significance between the two death rates.
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What the hell does this even mean?
 
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At this point I wouldn't trust anyone saying these drugs don't work because there's such a vested political interest in making sure they don't to own the big bad Orange Man. But maybe it doesn't. Who knows.

"The big takeaway for me from this study is that it's very consistent with the FDA and NIH guidelines that came out in April," said one of the study's senior authors, David Holtgrave, dean of the School of Public Health at the University at Albany. "When deciding on public health interventions and treatments for Covid-19 or any other disease, it's really important to follow the data and follow the science and make sure decisions are being made on the highest quality data possible."
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If only they showed such hesitation when they screamed at all the politicians and the media to lock down the world based on faulty models and questionable studies.
 
Save the Loli said:
At this point I wouldn't trust anyone saying these drugs don't work because there's such a vested political interest in making sure they don't to own the big bad Orange Man. But maybe it doesn't. Who knows.
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This is the essential problem. You honestly cannot trust any science that examines a social issue because it is so politicized, as is the peer review. Studies which show the negative aspects of transgenders are pulled.

All of it is a black box that none of us has the time or money to verify. It's sad, but a lot of science looks an awful lot like religion nowadays.
 
X Prime said:
This is the essential problem. You honestly cannot trust any science that examines a social issue because it is so politicized, as is the peer review. Studies which show the negative aspects of transgenders are pulled.

All of it is a black box that none of us has the time or money to verify. It's sad, but a lot of science looks an awful lot like religion nowadays.
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It's funny, the whole point of science's to encourage experimentation and to question things, yet there's so many people that actively discourage both.
 
This 87 cent a pill drug that has been around for 80 years and is commonly taken for a multitude of problems is actually super poison and nobody should take it and also don't take it because people need it.
But somehow the 1000 dollar a pill shit that shows a statistically insignificant improvement and has unknown long term effects is already flying through trials and it's ok to talk about how great it is.

And people accept this shit because orange man is bad.
 
Hmmm. . .this NIH study from 2005 concluded that in the case of the SARS coronavirus cloroquine and it's better tolerated analog hydroxycloroquine has "strong anti-viral effects" and these inhibitory effects were observed in cells treated both before and after exposure to the virus suggesting both prophylactic (preventative) and therapeutic advantage.
www.ncbi.nlm.nih.gov

Chloroquine is a potent inhibitor of SARS coronavirus infection and spread

Severe acute respiratory syndrome (SARS) is caused by a newly discovered coronavirus (SARS-CoV). No effective prophylactic or post-exposure therapy is currently available.We report, however, that chloroquine has strong antiviral effects on SARS-CoV infection ...
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
From what I've read over the years I wouldn't take a thing the AMA says at face value. I don't believe they are an objective apolitical organization and am fairly certain you can pay them to say shit, like if you are a corporation who magically has some "research" you've conducted that says everything is just fine and your product is great. If I remember the AMA's main goal is to increase the salaries of it's members a.k.a. doctors, rather than any real dedication to scientific truth and the advancement of medical technology for the benefits of all humans.
mises.org

100 Years of Medical Robbery | Dale Steinreich

Dale Steinreich explains the twin goals of the AMA-shaped medical industry: artificially elevated incomes and worship by patients.
mises.org mises.org
It took until 2002 for the AMA to admit that vitamin supplements promote general health and can act as a preventative for certain diseases.
The study is already flawed on it's surface because the only subjects were patients whose bodies were failing at fighting the virus to the point hospitalization was required, which would likely indicate a preponderance of individuals with underlying conditions and other complications. Hydroxycloroquine is best used as a prophylactic and in the early stages to prevent the virus from proliferating, not in end-stage patients to try to prevent death once all their systems have been compromised and their viral load is sky-high. It prevents the virus from spreading, once it's already there it doesn't kill it, it just prevents it from spreading further while your body fights what's already there. This is more disingenuous fear mongering. It's like standing there waiting until someones heart has been stopped for 20 minutes and then applying CPR and declaring that CPR is largly ineffective, doesn't prevent death whatsoever, and is probably dangerous.
 
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X Prime said:
All of it is a black box that none of us has the time or money to verify. It's sad, but a lot of science looks an awful lot like religion nowadays.
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The greatest problems for religion always happened when it got too political and became just another function of politics.
 
X Prime said:
This is the essential problem. You honestly cannot trust any science that examines a social issue because it is so politicized, as is the peer review. Studies which show the negative aspects of transgenders are pulled.

All of it is a black box that none of us has the time or money to verify. It's sad, but a lot of science looks an awful lot like religion nowadays.
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In a sane world, the effectiveness of an antiviral treatment would not be a social issue.
 
I wonder if the actions of the American leftwing during this flu season will be a wakeup call for all the big-brain centrists or if they'll just continue to shove things in their ass while waiting for the next marvel movie.
 
Save the Loli said:
At this point I wouldn't trust anyone saying these drugs don't work because there's such a vested political interest in making sure they don't to own the big bad Orange Man. But maybe it doesn't. Who knows.
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But you'd trust them if they said they worked, because Orange Man good?

It's really tough to do studies about if a drug works or not when the disease they are using resolves on its own (in most cases). The results of this study are pretty consistent with what studies done in other countries have said
 
Hollywood Hulk Hogan said:
But you'd trust them if they said they worked, because Orange Man good?

It's really tough to do studies about if a drug works or not when the disease they are using resolves on its own (in most cases). The results of this study are pretty consistent with what studies done in other countries have said
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It was an option that other countries were testing when we tried it out, it didn't work but it's image will always be good because it isn't as bad as the left exaggerated. Remember every major new source, excluding the icky fox, claimed a women that poisoned her husband with fish tank cleaner took the drug and two states banned it before it could be tested.



However, once the researchers statistically adjusted for the fact that the patients who took the drugs were sicker to start with, there was no statistical significance between the two death rates.
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What the hell does this even mean?
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The study is complete bullshit, they say later in the article that the drug is randomly handed out for the test yet this seems to state that anyone who was really sick was removed from the malaria drug group. Effectivley they removed any instances that didn't agree with their hypothesis until it gave them the result they wanted.
 
Hollywood Hulk Hogan said:
But you'd trust them if they said they worked, because Orange Man good?

It's really tough to do studies about if a drug works or not when the disease they are using resolves on its own (in most cases). The results of this study are pretty consistent with what studies done in other countries have said
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I'd suspect money over politics in this case. The medical establishment prefers the pill that costs 1000 times more, obviously. We should automatically be deeply suspicious of that.
 
Robert James said:
It was an option that other countries were testing when we tried it out, it didn't work but it's image will always be good because it isn't as bad as the left exaggerated.
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What? So it will always be good, even though it doesn't work, because it wasn't as bad as some people said it was?

Section230 said:
I'd suspect money over politics in this case. The medical establishment prefers the pill that costs 1000 times more, obviously. We should automatically be deeply suspicious of that.
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Except medical researchers, especially in other countries, don't have ties to that
 
You know, Academia is so shit I'm willing to believe that hydroxychloroquine does work but researchers purposely skew the results so they'll either be quoted by the media or to get back at Drumpf.
 
The entire argument this article goes on about is balancing on the soft, subtle, mealy mouthed statement that it doesn't fight the virus.

Of course it fucking doesn't actively fight the virus. It blocks the point of entry for the virus so the body's immune system can do the heavy lifting with the added benefit of lowering the risk of a cytokene storm. It's as much a therapeutic treatment as it is a prophylactic, and while it does both it works better as a preventative measure than post-infection treatment.

What's the term again? Oh. Right.

Fake goddamn news.
 
money hungry pharmacompanies combined with retraded Dems will kill americans if they dont stop this shit... It works and its pretty much free because bayer gave away giant amounts of it.
 
Dial M for Misgender said:
It almost seems like it was a mistake to deregulate pharma corps over the last 30+ years...
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I dont know who is behind this push, the realy evil companies are all giving away cheap pills for free.
Bayer is run by Sauron himself, and even they dont have the guts to push some unproven stuff over cheap and safe pills.
 
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