Source: https://www.axios.com/2024/07/31/gen-x-millennials-cancer-increase
Archive: https://archive.is/KL3en
6 hours ago - Health
A sweeping new study is widening the lens on a puzzling uptick in a range of cancers occurring among younger generations of patients.
Why it matters: It's the latest evidence that the burden of cancer could rise in the future despite major advances in treatment and prevention.
Archive: https://archive.is/KL3en
6 hours ago - Health
Gen X, millennials more likely to get cancer, new study shows
Tina ReedA sweeping new study is widening the lens on a puzzling uptick in a range of cancers occurring among younger generations of patients.
Why it matters: It's the latest evidence that the burden of cancer could rise in the future despite major advances in treatment and prevention.
- The study from the American Cancer Society found adults in their 30s, 40s and 50s are more likely than previous generations were to develop 17 different types of cancers, including breast, liver and pancreatic cancers.
- Previous research has indicated alarming increases in certain cancers among younger adults, such as colorectal cancer.
- A National Cancer Institute study published in June concluded Gen Xers were more likely to be diagnosed with cancer as they aged than previous generations, NPR reported in June.
- "But it definitely reflects what we've known and what we've noticed as well in our clinics," said Cercek, who wasn't involved in the study. "We really have no idea why."
- Of 34 cancers examined, half had increased incidence among younger adults, according to the study published Wednesday in The Lancet.
- Incidence of eight different cancers increased with each successive age cohort after 1920.
- In particular, adults born in the 1990 cohort were two or three times more likely to get cancers of the small intestines, kidney and pancreas (as well as the liver and bile duct in women) compared with those in born in the 1955 cohort at the same age.
- That's particularly concerning because it's "despite the fact that we have much better drugs for a lot of them," ACS chief scientific officer William Dahut told Axios.
- "It's still a much lower risk to have cancer in a young adult than someone over the age of 50," Dahut said.
- "However it can occur, and if you have a persistent symptom, and someone tells you, 'Well, you're too young for cancer,' that's not true."
- But the picture is likely more complicated.
- For instance, colorectal cancer is considered an obesity-related disease. But the historical rise in obesity doesn't always track with the uptick of disease in young people, Cercek said.
- Additionally, she said, doctors report commonly seeing younger colorectal cancer patients who are active and at a healthy weight.
- Ultraprocessed foods and the use of PFAS, known as "forever chemicals," are also being studied.
- But Dahut says genetic predisposition could be a key factor as well as early environmental exposures.
- It could drive a push toward more at-home testing for cancer and increase patient responsibility for understanding their personal risk and pursuing screening accordingly, Dahut said.
- One other potentially related trend to watch: how much anti-obesity medications impact risk for cancer and change future trends, Dahut said.